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Potter has had to make some difficult decisions before this summer's tournament, but he is able to call on two of last summer's marquee Premier League signings.
Liverpool forward Alexander Isak and Arsenal striker Gyokeres are expected to play key roles if Sweden are to progress, with matches against Tunisia, the Netherlands and Japan in Group F.
"I think they are different in their styles, which is good for us because you can hopefully use them effectively," said Potter.
"The honest truth is that we haven't played them together yet in my time, so that will be exciting to develop. If we can get them enjoying their football and firing, they are top players."
Isak has yet to start a match under Potter following an injury-hit season following his record £125m move from Newcastle to Liverpool last summer.
"It can take a bit of time," added Potter. "At the biggest clubs there is pressure and expectation, and when expectation and reality begin to diverge, it can create problems.
"His injuries have been disappointing, but I know him well. He is a top professional who wants to play and help his team."
Gyokeres, meanwhile, scored 21 goals as he won the Premier League title and reached the Champions League final in his first season after joining Arsenal from Sporting for £55m.
However, the former Coventry City forward, 27, has still faced criticism.
"It is a good example of the modern game," said Potter. "From our perspective, he has scored four goals in two matches and helped take us to the World Cup, so his impact has been significant."
He also recalled how Isak scored on his professional debut against his Ostersunds side at the age of 16 while playing for AIK.
As one of the last nations to qualify, Sweden were left with one of the remaining training bases among the 48 teams - SDJA, a high school facility in San Diego.
Potter said they have no complaints about the facilities, highlighting the increased importance of set-pieces in the heat and describing squad selection as involving the "toughest conversations as a father and human being".
Unlike England, who will base themselves in Miami before the tournament, Sweden will be based at home in Stockholm so players can spend time with family and friends to recharge after a long club season.
After friendlies against Norway and Greece, Sweden look forward to a return to the world's biggest stage against Tunisia on 15 June.
"My first football memory is from 1986 - I was 11, watching Diego Maradona," Potter reflected. "That was when I realised how special the game was. To work in that environment now is a dream."
